Kinetics of Recovery of the Dark-adapted Salamander Rod Photoresponse
نویسندگان
چکیده
منابع مشابه
Kinetics of Recovery of the Dark-adapted Salamander Rod Photoresponse
The kinetics of the dark-adapted salamander rod photocurrent response to flashes producing from 10 to 10(5) photoisomerizations (Phi) were investigated in normal Ringer's solution, and in a choline solution that clamps calcium near its resting level. For saturating intensities ranging from approximately 10(2) to 10(4) Phi, the recovery phases of the responses in choline were nearly invariant in...
متن کاملThe Role of Steady Phosphodiesterase Activity in the Kinetics and Sensitivity of the Light-Adapted Salamander Rod Photoresponse
We investigated the kinetics and sensitivity of photocurrent responses of salamander rods, both in darkness and during adaptation to steady backgrounds producing 20-3,000 photoisomerizations per second, using suction pipet recordings. The most intense backgrounds suppressed 80% of the circulating dark current and decreased the flash sensitivity approximately 30-fold. To investigate the underlyi...
متن کاملRecovery of the rod photoresponse in infants.
PURPOSE To study deactivation of the rod photoresponse in infants using a paired-flash procedure. Rhodopsin content increases and scales the parameters of the activation of rod phototransduction as rods develop. However, little is known about the kinetics of deactivation in the rods of young infants. METHODS ERG responses to pairs of flashes were used to study the recovery of the rod response...
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The single photon response (SPR) in vertebrate phototransduction is regulated by the dynamics of R* during its lifetime, including the random number of phosphorylations, the catalytic activity and the random sojourn time at each phosphorylation level. Because of this randomness the electrical responses are expected to be inherently variable. However the SPR is highly reproducible. The mechanism...
متن کاملRecovery of the rod photoresponse in infant rats
We tested the hypothesis that the kinetics of recovery of the rod photoresponse differ between mature and immature rods. A paired flash paradigm was used. The effect of a test flash on the ERG a-wave response to a probe flash presented 60 to 2 s after the test flash was studied. The functions summarizing the interaction between the test and probe flash did not differ significantly between infan...
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ژورنال
عنوان ژورنال: Journal of General Physiology
سال: 1998
ISSN: 0022-1295,1540-7748
DOI: 10.1085/jgp.111.1.7